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Game Details

Release name : S.E.M.I. – Side Effects May Include Build 02022026 + ONLINE
Size : 1.13 GB

Title : S.E.M.I. – Side Effects May Include…

Genre : Action, Indie

Developer : Two Horn Unicorn

Publisher : Two Horn Unicorn

Store : click here

Release Date : 23 Jan, 2026

Credits / Released By: OFME

Screenshots

Gameplay

About This Game :

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here, you and up to 3 of your brainless loyal friends play as patients, fighting staff and other patients while stumbling into all sorts of unexpected situations. Brawls, side-effect pills, and brutal platforming will absolutely challenge your clumsy friends’ hands sense of teamwork. Expect obstacles, puzzles, deadly traps, and rooms where a single wrong move can knock out the entire squad.

Communicate in voice chat and arrange sabotage help your friends pass through rooms, get out of traps and fight with opponents! In your arsenal: close combat, physics, amazing abilities and … imagination!

Take pills and get abilities:

• Bipolar force is an invulnerable monster, then a helpless rag!

• Laser astigmatism — two sights, one laser… Where will he shoot?

• Stendhal syndrome — are you looking at a painting? Now you’re hysterical and destroying everything around you!

• Alice’s syndrome is either tiny or gigantic — have time to adjust!

Madness is near! You and your friends can go crazy and start running, jumping and fighting, and your abilities will become uncontrollable. Do you want to take back control? Take the pills 🙂

Locations are randomly generated from rooms with changing gravity, traps, moving walls, and other “pleasant” surprises.

After a successful escape, you will receive a medical report: “The patient was stable until he started hitting the guards with a bottle. Diagnosis: Overmotivation” or something worse!

Unlock new costumes and decorations. Let each new escape be more stylish than the previous one!

Will you and your friends be able to escape… or at least not go crazy?

Welcome to the mental hospital! Here, your abilities are a lottery, and your friends can be the most dangerous opponents!

System Requirements for S.E.M.I. – Side Effects May Include…

MINIMUM :

• OS: Windows 10
• Processor: Intel Core i5 series or Ryzen series
• Memory: 8 GB RAM
• Graphics: GTX 960 or AMD R9 290
• DirectX: Version 11
• Storage: 3 GB available space

RECOMMENDED :

• OS: Windows 11
• Processor: Intel Core i7 series or Ryzen series
• Memory: 8 GB RAM
• Graphics: GTX 1660 or RX6600
• DirectX: Version 12
• Storage: 3 GB available space

How To Install S.E.M.I. – Side Effects May Include…

1. Download The Game.
2. Extract with WinRAR
3. Play!.

How To play S.E.M.I. – Side Effects May Include… ONLINE

1. Download the “Online Crack” from the link provided below and extract the files. After extraction, move the contents into your game’s main installation directory.

2. Download and install Steam.

3. Open Steam and log in. If you don’t have an account yet, you can create one through HERE.

4. Press “Win + R” on your keyboard, type “steam://install/480”, and hit Enter. This will install and update the required game component.

5. Launch the game via SEMI.exe.

6. Joining: Accept an invitation from a friend.

Hosting: Play > Host Game > ESC > Invite Friends > We invite friends and wait for them to connect.

7. Enjoy !

Note:

• The game already comes with the “Online Crack” pre-applied, so you can skip Step #1 mentioned above. However, if your antivirus software removes the “Online Crack” files, you’ll need to reapply them manually.